Vitamin B Complex

chemical compounds

admin

Oct 4, 2023 - 03:27

0 18

Thiamin, also known as vitamin B1 (or thiamine), is a heterocyclic compound that contains a thiazole ring, which is a five-membered ring made up of one sulfur atom, one nitrogen atom, and three carbon atoms.

vitamin B complex, several vitamins that traditionally have been grouped together because of loose similarities in their properties, their distribution in natural sources, and their physiological functions, which overlap considerably. All the B vitamins, like vitamin C, are soluble in water, in contrast to the fat-soluble vitamins A, D, E, and K.

Most of the B vitamins have been recognized as coenzymes (substances that participate with enzymes in accelerating the interconversion of chemical compounds), and they all appear to be essential in facilitating the metabolic processes of all forms of animal life. The complex includes pantothenic acid, niacin, biotin, folic acid, riboflavin (vitamin B₂), thiamin (vitamin B₁), vitamin B₆, and vitamin B₁₂ (cobalamin). The compounds carnitine, choline, lipoic acid, inositol, and para-aminobenzoic acid perform analogous functions in animals and have been included among the B vitamins by certain authorities. See table of the vitamins.

The vitamins
vitamin	alternative names/forms	biological function	symptoms of deficiency
Water-soluble
thiamin	vitamin B₁	component of a coenzyme in carbohydrate metabolism; supports normal nerve function	impairment of the nerves and heart muscle wasting
riboflavin	vitamin B₂	component of coenzymes required for energy production and lipid, vitamin, mineral, and drug metabolism; antioxidant	inflammation of the skin, tongue, and lips; ocular disturbances; nervous symptoms
niacin	nicotinic acid, nicotinamide	component of coenzymes used broadly in cellular metabolism, oxidation of fuel molecules, and fatty acid and steroid synthesis	skin lesions, gastrointestinal disturbances, nervous symptoms
vitamin B₆	pyridoxine, pyridoxal, pyridoxamine	component of coenzymes in metabolism of amino acids and other nitrogen-containing compounds; synthesis of hemoglobin, neurotransmitters; regulation of blood glucose levels	dermatitis, mental depression, confusion, convulsions, anemia
folic acid	folate, folacin, pteroylglutamic acid	component of coenzymes in DNA synthesis, metabolism of amino acids; required for cell division, maturation of red blood cells	impaired formation of red blood cells, weakness, irritability, headache, palpitations, inflammation of mouth, neural tube defects in fetus
vitamin B₁₂	cobalamin, cyanocobalamin	cofactor for enzymes in metabolism of amino acids (including folic acid) and fatty acids; required for new cell synthesis, normal blood formation, and neurological function	smoothness of the tongue, gastrointestinal disturbances, nervous symptoms
pantothenic acid		as component of coenzyme A, essential for metabolism of carbohydrate, protein, and fat; cofactor for elongation of fatty acids	weakness, gastrointestinal disturbances, nervous symptoms, fatigue, sleep disturbances, restlessness, nausea
biotin		cofactor in carbohydrate, fatty acid, and amino acid metabolism	dermatitis, hair loss, conjunctivitis, neurological symptoms
vitamin C	ascorbic acid	antioxidant; synthesis of collagen, carnitine, amino acids, and hormones; immune function; enhances absorption of non-heme iron (from plant foods)	swollen and bleeding gums, soreness and stiffness of the joints and lower extremities, bleeding under the skin and in deep tissues, slow wound healing, anemia
Fat-soluble
vitamin A	retinol, retinal, retinoic acid, beta-carotene (plant version)	normal vision, integrity of epithelial cells (mucous membranes and skin), reproduction, embryonic development, growth, immune response	ocular disturbances leading to blindness, growth retardation, dry skin, diarrhea, vulnerability to infection
vitamin D	calciferol, calatriol (1,25-dihydroxy vitamin D₁ or vitamin D hormone), cholecalciferol (D₃; plant version), ergocalciferol (D₂; animal version)	maintenance of blood calcium and phosphorus levels, proper mineralization of bones	defective bone growth in children, soft bones in adults
vitamin E	alpha-tocopherol, tocopherol, tocotrienol	antioxidant; interruption of free radical chain reactions; protection of polyunsaturated fatty acids, cell membranes	peripheral neuropathy, breakdown of red blood cells
vitamin K	phylloquinone, menaquinone, menadione, naphthoquinone	synthesis of proteins involved in blood coagulation and bone metabolism	impaired clotting of the blood and internal bleeding